Pharmaceutical Breakthroughs is dedicated to fostering a deep understanding of novel developments, advancements, and breakthroughs in the field of pharmaceutical sciences. Our journal aims to be a platform for researchers, scientists, clinicians, and industry professionals to share their insights, discoveries, and perspectives in the realm of pharmaceutical innovation.
Volume 1
Issue 1
Page: [8 - 16]
Published Online: 10 Nov 2023
This abstract summarises the studies on the use of umbilical cord stem cells to treat Prader-Willi syn- drome. Among the various stem cells found in the umbilical cord, hematopoietic and mesenchymal stem cells may create bioactive molecules that aid in tissue repair and regeneration, control immunological responses, and give birth to a variety of cell types. Because of this, they present a feasible option for treating the multidisciplinary character of PWS. Preclinical research on PWS animal models has shown promising outcomes, with umbilical cord stem cell transplantation improving metabolic disorders, hy- pothalamic function, and general behavior. It has been investigated if immunological regulation, trophic support, and paracrine signaling are among the factors that promote stem cell therapeutic potential. Several clinical studies employing umbilical cord stem cells to treat PWS are now underway, and the findings should aid in assessing the advantages and disadvantages of using this approach on patients. The preliminary evidence is encouraging, since some trial participants improved in hyperphagia, mus- cular tone, and cognitive ability. Although the use of umbilical cord stem cells as a PWS treatment has shown some promise, further study is required to determine its long-term safety, optimal dose, and ongoing effectiveness. A variety of key elements, such as ethical issues, regulatory frameworks, and the availability of standardized stem cell products, will have a considerable impact on the future development of this treatment technique. SD is a disease known as a neurodevelopmental problem represented through problems with social communication, sensor sensitivity, and repetitive behaviors. Despite years of study, therapy options for autism spectrum disorder (ASD) remain relatively limited. As regenerative medicine has improved, stem cell treatment has been investigated as a novel thera- peutic option for the underlying neurological disorders that underpin ASD. The development, possible methods, and potential uses of stem cell treatment for autistic children are discussed in this article.
Keywords: Prader-Willi Syndrome, Umbilical Cord Stem Cells, Stem Cell Therapy, Genetic Disorder, Multi-Systemic Improvements, Preclinical Studies, Clinical Trials, Hypothalamic Function, Behavioral Manifestations
Umbilical Cord Stem Cell Stem Cell Therapy For Rare Genetic Disease Prader-Willi Syndrome. Pharmaceutical Breakthroughs, 1(1), 8 - 16. doi.org/10.59762/pb724290251120231110130643
(2023).At Guinness Press, authors retain the copyright for all articles published in our journals. These articles are licensed under the open-access Creative Commons CC BY 4.0 license, granting free access for reading and download. Additionally, the original published version must be appropriately cited when reusing or quoting the article. These terms ensure widespread accessibility while ensuring proper attribution to the authors.
All content published by Guinness Press is safeguarded by international copyright and intellectual property regulations. We kindly request that you honor these protections when utilizing our materials.
For further information, please contact us at info@guinnesspress.org.
Author(s): Munzallin Munaf
Article | Published Online: 05 Oct 2023 | Pages [1 - 8]
Read MoreAuthor(s): Mark Treve
Article | Published Online: 05 Oct 2023 | Pages [17 - 26]
Read MoreAuthor(s): Nilubon Sivabrovornvatana
Article | Published Online: 09 Oct 2023 | Pages [56 - 66]
Read More